I recently started playing Don't Starve again, specifically Shipwrecked. I remembered how annoying the poison was when I last played it, so I turned the poison off before generating the world. Now I wish I hadn't because it's not as bad as I thought it was and the poison-related items that I have are completely useless.
Is it possible to change a setting that doesn't involve structures (in this case: turning on/off poison) after the world is generated? (preferably without a mod) Can this be done with the console or do I have to change something in the code of the save file?