When worn, it protects the player character from getting Poisoned by gas cloud attacks of Poisonous Holes and Stink Rays. However, it offers no protection against Poisoning via physical attacks of Poison Snakes, Poison Mosquitoes, or Spider Warriors.
In the Hamlet (HAM) DLC, the Particulate Purifier will grant immunity to the toxic gas in the Gas Rainforest, as well as the Noxious Cloud created by using the Bug B'Gone. It does not, however, grant protection against the effects of Hay Fever.
- WX-78 is immune to poison, therefore wearing a Particulate Purifier gives no benefits outside of Hamlet.
- The Particulate Purifier renders the Stink Rays completely harmless, making Stink Ray spawns a very good source of Monster Meat.
- Prior to the "Seas The Day!" update, this item was simply called "The Gas Mask", which functioned identically, except for a slightly different recipe and texture. Its description was "Why smell bad smells?", and it cost 2 Empty Bottles, 1 Cloth, and 1 Jellyfish.
- The Gas Mask also had a voice filter which would increase the pitch of a character's voice when saying something.
- The concept of the Gas Mask is reused in HAM, bearing a large visual resemblance as well as sharing the same name.