Guano is an item dropped by Batilisks and is similar to Manure, except it is grayish-white in color. It can occasionally be found where Batilisks are commonly found, such as near unplugged Sinkholes and on Stalagmite Terrain.
Guano is 1.5× more effective than Manure when used as a fertilizer, although it cannot be used to craft Farm plots. It creates an aesthetic gas cloud when used as a fuel source.
In Don't Starve Together, the player has a 33% chance to receive Guano by feeding Seeds to a Bird in a Birdcage. It will, however, appear much smaller than the Guano dropped by Batilisks.