The Alchemy Engine is the tier 2 Science station. It requires a Science Machine to prototype for all characters except Wickerbottom, and costs 4 Boards, 2 Cut Stones, and 6 Gold Nuggets to craft. Prototyping an Item using the Alchemy Engine will increase Sanity by 15.
See also: Crafting
In the Shipwrecked DLC, the Alchemy Engine can be flooded.
- The Alchemy Engine is able to unlock Tier 1 items without the need for a nearby Science Machine, so it may be beneficial to break down the Science Machine for resources after building it.
- Since Wickerbottom has Tier 2 items unlocked with the Science Machine, this machine is only necessary for crafting her book On Tentacles.
- In the early Beta version of Don't Starve, the game used a "Research Points" system, instead of prototyping. Crafting this station cost 200 Research Points.
- As of the Hungry For Your Hunger update, Tier 3 recipes crafted using the Shadow Manipulator have been moved to the Alchemy Engine, due to the separation of Science and Magic.