Guides/Wickerbottom

Advantage
Main article: Wickerbottom
 * Can craft all Science Machine receipes without a prototype (without needing it).
 * Can prototype all Alchemy Engine receipes with a Science Machine.

Disadvantage
Main article: Wickerbottom
 * Cannot sleep (Tent, Straw Roll, Fur Roll).
 * Suffers extra from Spoilage.

Finding a home
When settling somewhere you should think about your sanity sources and food management. You already have access to all Science Machine receipes, this allows you to delay settling and roam around for a little longer.
 * Since you cannot sleep, you need a source of sanity other than Tent. Spider dens are a nice source of silk, which can be used to craft clothing that restore sanity, in addition to that, Mushrooms (Green and Blue) are a nice source of Sanity, while you don't have a base yet, open all Sink Holes, have a look in the caves and see if there are any green or blue Mushtree Forests nearby, if there are, consider building your base near the Sink Hole (some distance away because Batilisks spawn from it).

Managing food

 * Food spoilage cannot be afforded, therefore, try not to grab more than you need and avoid quickly spoiling foods unless you will eat them immediately. Leaves Berries on their bushes and Carrots on the ground for emergencies, because they will not spoil unless picked up, also leave Koalefants and other animals alive until you need them, do not have mercy on Spiders however, because you need the Silk, Cooked Monster meat doesn't spoil fast, and Spiders respawn fast.
 * Getting an Ice Box is a high priority. It will delay the spoilage of your food, as well as your Mushrooms, which are equally important, it also stores your Ice indefinately. While you are scouting, look for sources of Gears, grab as many as you can.